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GW-501516 (GW1516, Endurobol or GSK-516) acts as a PPAR-β modulator. GW 501516 activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and GW-501516 has been demonstrated to reverse metabolic abnormalities in obese mice with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation.
- PPAR-β modulator
- Agitate bottle before each administration
- Not for human consumption
GW50156 regulates fat burning through a number of mechanisms. It increases glucose uptake in skeletal muscle tissue and increases muscle gene expression, especially genes involved in preferential lipid utilization. This shift changes the body's metabolism to favor burning fat for energy instead of carbohydrates or muscle protein, potentially allowing clinical application for obese patients to lose fat effectively without experiencing muscle catabolism or the effects and satiety issues associated with low blood sugar. GW-501516 also increases muscle mass, which improved glucose tolerance and reduced fat mass accumulation even in mice fed a very high fat diet, suggesting that GW-501516 may have a protective effect against obesity.
It has been demonstrated at an oral doses of just 5 mg a day to reverse metabolic abnormalities in obese mice with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation. Treatments with GW-501516 have been also shown to increase HDL cholesterol by up to 79% in rhesus monkeys and the compound is now undergoing Phase II trials to improve HDL cholesterol.
M.Wt: 453.498
Formula: C21H18F3NO3S2
Solubility: DMSO/CMC
Purity: >99%
Storage: at 20? 2 years
Half life: 24 hours
CAS No.: 317318-70-0
THIS PRODUCT IS NOT INTENDED TO TREAT, CURE OR DIAGNOSE ANY CONDITION OR DISEASE AND IS NOT FOR HUMAN CONSUMPTION
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Product Categories : Sarms Liquid
