Company Details
Shaanxi YXchuang Biotechnology Co., Ltd
Unit Price: | USD 2 - 3 / Gram |
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Payment Type: | L/C,T/T,D/P,D/A,Paypal |
Incoterm: | FOB,DDP,DEQ,CIP,FCA,CPT,FAS,DES,DAF,EXW,CFR,Express Delivery,CIF,DDU |
Model No.: YXchuang-gvs 111
Brand: YXchuang
Place Of Origin: China
Types Of: Agrochemical Intermediates
Color: White
Appearance: White Powder
Purity: 99%min
Shelf Life: 2 Years
Storage: Cool Dried Storage
Grade: Phamaceutical Grade
Payment Term: Tt.Western Union .Credit C
Test Method: Coa
Usage: Nootropics
Product Name: Gvs 111
Packaging: aluminium foil bag
Productivity: 100000kg
Transportation: Land,Ocean,Air,Express
Place of Origin: china
Supply Ability: 1000000
Certificate: ISO COA
HS Code: YXchuang
Port: Any port
Payment Type: L/C,T/T,D/P,D/A,Paypal
Incoterm: FOB,DDP,DEQ,CIP,FCA,CPT,FAS,DES,DAF,EXW,CFR,Express Delivery,CIF,DDU
Noopept (GVS-111) is a medication promoted and prescribed in Russia and neighbouring countries as a nootropic.IC50 Value:Target: in vitro: Nooglutil exhibits pharmacologically significant competition with a selective agonist of AMPA receptors ([G-3H]Ro 48-8587) for the receptor binding sites (with IC50 = 6.4 +/- 0.2 microM), while the competition of noopept for these receptor binding sites was lower by an order of magnitude (IC50 = 80 +/- 5.6 microM). GVS-111 significantly increased neuronal survival after H(2)O(2)-treatment displaying a dose-dependent neuroprotective activity from 10 nM to 100 microM, and an IC(50) value of 1.21+/-0.07 microM. GVS-111 inhibited the accumulation of intracellular free radicals and lipid peroxidation damage in neurons treated with H(2)O(2) or FeSO(4), suggesting an antioxidant mechanism of action.in vivo: N-Phenylacetyl-L-prolylglycine ethyl ester (GVS-111) administered intravenously at a dose of 0.5 mg/kg/day, for the first time 1 h after ischaemic lesion and then for 9 post-operative days, with the last administration 15 min before testing, attenuated the deficit. GVS-111 itself was not found in rat brain 1 h after 5 mg/kg i.p. administration up to limit of detection (LOD) under high performance liquid chromatography (HPLC) conditions. The most pronounced antiinflammatory effect of dipeptide was observed on the model of adjuvant arthritis in rats, where the drug administered over 25 days in a daily dose of 0.5 mg/kg (i.m.) or 5 mg/kg (p.o.) significantly reduced the chronic immune inflammation (on the 12th day, by 94.0 and 74.1%, respectively).Toxicity: Noopept administered in this dose range induced no irreversible pathologic changes in the organs and systems studied and exhibited no allergenic, immunotoxic, and mutagen activity. Clinical trial: Discontinued
Product Name | Noopept |
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Cas No. | 157115-85-0 |
Density | 1.2±0.1 g/cm3 |
Boiling Point | 547.3±50.0 °C at 760 mmHg |
Melting Point | 94.0 to 98.0 °C |
Molecular Formula | C17H22N2O4 |
Molecular Weight | 318.368 |
Flash Point | 284.8±30.1 °C |
Exact Mass | 318.157959 |
PSA | 75.71000 |
LogP | 1.28 |
Vapour Pressure | 0.0±1.5 mmHg at 25°C |
Index of Refraction | 1.549 |
About us:
Company Profile:
Our company offers variety of products which can meet your multifarious demands.including API Powder、Pharmaceutical Intermediates、Vitamins Powder、Plant Extracts、Food Additive、Peptide Powder and so on We adhere to the management principles of "quality first, customer first and credit-based" since the establishment of the company and always do our best to satisfy potential needs of our customers. Our company is sincerely willing to cooperate with enterprises from all over the world in order to realize a win-win situation since the trend of economic globalization has developed with anirresistible force.
Certification:
Payment Term and Packing Delivery:
FAQ:
Q1: Are you a manufacturer?
Answer: Yes
Q2: How to contact with us?
Click the Google "Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or online ,nomal order by T/T to our company account
Q4:Can you give me a discount price?
Surely,It depend on your qty
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us,
we will send you free goods for replacement or refund your loss.
Product Categories : Nootropic Powder > Phenibut HCL