Oxytocin is a peptide hormone secreted by the posterior pituitary, synthesized by the paraventricular and supraoptic nuclei of the hypothalamus, and composed of nine amino acids, which are transported to the neuropituitary gland for release at a rate of 2 mm to 3 mm per day. Cysteine (Cys) residues at positions "1" and "6" form a 6-peptide ring in the form of disulfide bonds.
Oxytocin has stimulating mammary gland secretion of milk, in the process of childbirth to promote the contraction of uterine smooth muscle, promote maternal love. In addition, it reduces the levels of stress hormones such as adrenoketone in the body to lower blood pressure. It is not exclusive to women and can be produced by both men and women
COA:
Function：(1) the role of the mammary gland: lactating mammary gland under the action of prolactin continuously secrete milk, stored in the mammary gland acini. Oxytocin can make the myoepithelioid cells around the mammary gland acinar contraction, promote the function of milk secretion of the mammary gland. (2) Effect on the uterus: oxytocin has a strong effect on the uterus, but the pregnant uterus is more sensitive. Estrogen increases the sensitivity of the uterus to oxytocin, while progesterone does the opposite.
(3) The effect on social shyness and autism: oxytocin can help people who are shunned in social situations due to shyness overcome social shyness. But oxytocin doesn't work for people who are already confident.
(4) When the mood is cheerful or there is a strong sense of belonging, the hypothalamus synthesizes oxytocin, the pituitary secretes oxytocin, and the pressure is relieved. At the same time, the supply of oxygen to tissues in the body increases dramatically.
Secretion regulation
The secretion of oxytocin is mainly regulated by neural reflexes. When the baby sucks the nipple, the stimulus information is transmitted to the supraoptic nucleus and paraventricular nucleus of the hypothalamus, causing the secretion of oxytocin, so that the breast ejection, known as the ejection reflex, belongs to the neuroendocrine reflex. On this basis, a conditioned reflex can be formed, and the baby's cry or touch can cause ejection.
During labor, the cervix and vagina are compressed and pulled, which reflexively causes the secretion of oxytocin, which helps labor. Although oxytocin can stimulate uterine contractions, it is not the determinant in triggering contractions in labor. In addition, emotional reactions such as panic and anxiety can inhibit oxytocin secretion
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