Company Details
Shaanxi YXchuang Biotechnology Co., Ltd
Unit Price: | USD 49 - 99 / Kilogram |
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Payment Type: | L/C,T/T,D/P,Paypal |
Incoterm: | FOB,CFR,CIF,EXW,FCA,CPT,CIP |
Model No.: YXchuang-Thymosin Beta 4 Acetate
Brand: YXchuang
Place Of Origin: China
Types Of: Agrochemical Intermediates, Syntheses Material Intermediates
Shelf Life: 2 Years
Form: Powder
Packaging: Drum
Solubility: Soluble In Hot Water, Hot Ethanol
Grade: Phramaceutical Grade
Product Name: Thymosin Beta 4 Acetate
Type: Phramaceutical Grade
Appearance: White Freeze-Dried Powder
Color: White Freeze-Dried Powder
Part: Phramaceutical Grade
Packaging: aluminium foil bag
Productivity: 100000kg
Transportation: Ocean,Land,Air,Express
Place of Origin: china
Supply Ability: 1000000
Certificate: ISO COA
HS Code: YXchuang
Port: Any Port
Payment Type: L/C,T/T,D/P,Paypal
Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
Tβ4 is one of the main actin regulatory molecules in human body. It has multiple biological functions and plays an extremely important role in physiological and pathological processes such as tissue regeneration, remodeling, wound healing, maintenance of actin balance, tumor pathogenesis and metastasis, apoptosis, inflammation, angiogenesis, hair follicle development and so on. 1. Actin regulator Actin accounts for about 10% of total protein in non-muscle cells and is an important component for cell structure, cell movement and wound healing. Tβ4 in cells is sufficient to block all actin and can be involved in the regulation of actin polymerization and depolymerization. Tβ4 can bind actin monomer at a ratio of 1:1 to prevent the formation of F-actin polymeric body. The binding of Tβ4 to actin is accompanied by dissociation of binding water, and its C-terminus binds to actin His-40, resulting in the conformation change of actin monomer. The molecular structure of Tβ4 contains a Chemicalbook actin binding domain (LKKTET), which is the main electrostatic contact site. Its N-terminal profragment can inhibit the polymerization of actin by steric action. When acted alone, Tβ4 can inhibit the polymerization of actin and the exchange of nucleosides on actin. This is in contrast to the effect of Profiling, another actin-binding protein, which can promote the exchange of ADP and ATP and accelerate the assembly of actin. Tβ4 and Profiling can cooperatively regulate the assembly of actin. Tβ4 regulates the conversion between G-actin and F-actin. Tβ4 concentrations up to 300pmol have been reported in highly mobile blood cells, whereas tβ4 binding to g-actin requires less than 20pmol. When the concentration of Tβ4 increased, the depolymerization ability of F-actin decreased, which may be the reason for the function of Tβ4 in regulating the intracellular microfilament system.
CAS No.:77591-33-4 Molecular Formula: C212H350N56O78S Molecular Weight:4963.4408g/mol Purity : 98% HPLC
COA:
Function:1. Thymic β4 and tumor studies have shown that thymic β4 acetate is associated with a variety of tumors, including colon cancer, melanoma, fibrosarcoma, breast cancer, pancreatic cancer and lung cancer, etc. It can cooperate with a variety of factors to promote tumor invasion and metastasis. 2. The role of Chemicalbook thymus β4 in the repair of heart injury in the acute phase of myocardial infarction, a large number of cardiomyocytes are ischemic and necrotic, leading to the impairment of cardiac function, and eventually progress to heart failure. Studies have confirmed that acetic acid thymic β4 has the protective effect on cardiomyocytes.
Peptide series:Peptide products and API Products are loved by people all over the world like Sams products! Related products:Besides Peptide Powder, raw pharmaceutical powder, puzzle powder and Plant Extract are also popular
About us:
Our company offers variety of products which can meet your multifarious demands.including API Powder、Pharmaceutical Intermediates、Vitamins Powder、Plant Extracts、Food Additive、Peptide Powder and so on We adhere to the management principles of "quality first, customer first and credit-based" since the establishment of the company and always do our best to satisfy potential needs of our customers. Our company is sincerely willing to cooperate with enterprises from all over the world in order to realize a win-win situation since the trend of economic globalization has developed with anirresistible force.
Payment Term and Packing Delivery:
FAQ:
Q1: Are you a manufacturer?
Answer: Yes
Q2: How to contact with us?
Click the Google "Contact Supplier" And then send us message the product you interest in, you will get reply within 24 hours.
Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or online ,nomal order by T/T to our company account
Q4:Can you give me a discount price?
Surely,It depend on your qty
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us,
we will send you free goods for replacement or refund your loss.
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