Product Introduction:
Sermorelinacetate is a synthetic growth hormone releasing hormone (gh) with 29 amino acid polypeptide. It is the amino terminal fragment of endogenous gh Chemicalbook(GHRH) and has significant growth regulation effect. Blacklock et al. proposed that neuropeptides/neurotransmitters, hormones and cytokines are the internal components of the nervous system
| Product Name | S'ermorelin. Acetate; GRF 1-29 |
| Cas No. | 86168-78-7 |
| Sequence | H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2 |
| Molecular Formula | C149H246N44O42S |
| Molar Mass | 3357.88 g/mol |
| Purity | ≥98% |
| Impurity | ≤0.5% |
| Storage Temperature | 2-8ºC |
Function: Sermorelin acetate is a synthetic peptide different from GHRH that stimulates the release of growth hormone from the pituitary gland. The results showed that sermorelin acetate could antagonize the immunosuppression induced by cyclophosphamide in mice. The body's immune system, the macrophages in specific and nonspecific cellular immune function and immune regulation plays an important function of acetate Murray house forests in immunocompromised mice immune organ thymus and spleen weight increased significantly, improve the phagocytosis of mononuclear phagocytes, tip can strengthen the nonspecific immune function in mice. Cyclophosphamide could inhibit the proliferation of T lymphocytes, while chemorelin acetate could significantly counter the toxic effect of CY on T lymphocytes and restore the proliferation of T lymphocytes. Two nitrochlorobenzene (DNCB) [6] is a kind of haptens, once the infiltration of the skin with skin protein combined into complete antigen, stimulate T lymphocyte proliferation in sensitization lymphocytes, again contact DNCB produce delayed-type hypersensitivity, via the ear swelling degree can determine the cell immune function, acetate shed Murray forests in immunosuppressive mice ear swelling degree increase. At the same time, it can also increase the content of IL-2, which is mainly produced by T lymphocytes, so it can also indirectly reflect the function of cellular immunity.
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HGH, 191AA, growth hormone, etc
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