Product Introduction:
Synthetic growth hormone releasing peptides have strong growth hormone releasing effects and many other biological activities. Recent studies have found that peptide GHS have significant cardiovascular effects. In this study, hexarelin, one of the synthetic growth hormone releasing peptides, was selected to study the effects of Hexarelin on cardiomyocyte apoptosis, cardiomyocyte hypertrophy and atherosclerosis in the process of heart failure from the holistic, cellular and molecular levels through in vitro and in vivo experiments. Firstly, in the first and second part of the experiment, we studied the effect of Hexarelin on the apoptosis of cardiomyocytes induced by Ang ⅱ in primary culture of neonatal rats and the effect of four kinds of GHRP on the apoptosis of cardiomyocytes in heart failure rats in vitro and in vivo.
| Product name | Hexare lin Acetate |
| Other name | Hexare lin Acetate, HEX, Examore lin |
| CAS No | 140703-51-1 |
| Molecular formula | C47H58N12O6 |
| Molecular Weight | 887.04022 |
| Type: | 2mg/vial |
| Apperance: | white powder |
| Assay | 99% |
Function：The results showed that Hexarelin significantly inhibited the apoptosis of cardiomyocytes induced by Ang ⅱ, and the four GHRP significantly improved the cardiac function and inhibited the apoptosis of cardiomyocytes in stress-burdened heart failure rats. The mechanism may be related to inhibiting the activity of caspase-3 enzyme, inhibiting the expression of Bax mRNA, increasing the expression of Bcl-2 mRNA and inhibiting the expression of p38MAPK protein. In view of the obvious therapeutic effect of GHRP on heart failure rats, and cardiac hypertrophy is one of the important pathogenesis of heart failure, the effect of Hexarelin on Ang ⅱ induced cardiac hypertrophy and the effect of Hexarelin on SHR cardiac hypertrophy were observed in the third part. The results suggest that Hexarelin has significant anti-ANG ⅱ induced myocardial hypertrophy and inhibition of SHR myocardial hypertrophy. The mechanism is related to the inhibition of AT1 receptor mRNA expression, the up-regulation of AT2 receptor mRNA expression and the inhibition of ERK1/2 activity. As you can see from the previous three experiments, Hexa
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HGH, 191AA, growth hormone, etc
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Steroid, bodybuilding oil, bodybuilding peptide, veterinary medicine, Food Additive, Cosmetic Peptide, API, Plant Extract, puzzle medicine, health care products
About us:
Our company offers variety of products which can meet your multifarious demands. including API Powder、Pharmaceutical Intermediates、Vitamins Powder、Plant Extracts、Food Additive、Peptide Powder and so on We adhere to the management principles of "quality first, customer first and credit-based" since the establishment of the company and always do our best to satisfy potential needs of our customers. Our company is sincerely willing to cooperate with enterprises from all over the world in order to realize a win-win situation since the trend of economic globalization has developed with anirresistible force.
Company Profile:
Our company offers variety of products which can meet your multifarious demands.including API Powder、Pharmaceutical Intermediates、Vitamins Powder、Plant Extracts、Food Additive、Peptide Powder and so on We adhere to the management principles of "quality first, customer first and credit-based" since the establishment of the company and always do our best to satisfy potential needs of our customers. Our company is sincerely willing to cooperate with enterprises from all over the world in order to realize a win-win situation since the trend of economic globalization has developed with anirresistible force.
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FAQ:
Q1: Are you a manufacturer?
Answer: Yes
Q2: How to contact with us?
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Q3:Which kind of payment terms do you accept?
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Q4:Can you give me a discount price?
Surely,It depend on your qty
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us,
we will send you free goods for replacement or refund your loss.
Product Categories : Peptides Products > HGH Products
